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More Than Just Weight Loss: How GLP-1 Agonists Evolved from Diabetes Drugs to a New Class of Metabolic Medicines When GLP-1 receptor agonists (GLP-1RAs) were first approved over a decade ago, their primary indication was simple: help people with Type 2 diabetes manage their blood sugar

Study of More Than 110,000 Women Finds Lower Breast Cancer Rates The research team reviewed electronic health records from 111,646 women between the ages of 45 and 80 who had a body mass index (BMI) of 25 or higher and underwent breast imaging within the Penn Medicine health system between January 2022 and June 2025

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They found that the drug semaglutide could protect these cells from damage