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These activities encompass functioning as a protease [12], associating with the enzyme adenosine deaminase (ADA) [13], extracellular matrix interaction [14], serving as a cell surface coreceptor for the entry of viruses [15], and modulation of signal transduction intracellularly, thereby influencing the migration of cells and reproduction [16]

Together, these developments underscore the dynamic interplay between medical advances, social attitudes, and the lived experiences of individuals with obesity, highlighting the need for continued dialog around the ethical, cultural, and clinical implications of obesity treatment

MASLD: metabolic dysfunction-associated steatotic liver disease