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According to NICE guideline NG198 on acne management, first-line options include fixed-combination topical treatments such as adapalene with benzoyl peroxide or benzoyl peroxide with clindamycin
Siglioccolo A, Petrosino G, Galardo A, Vinciguerra C, Romanelli A, Gammaldi R
In all cases, patients experienced transient dystonia following BTA injections, with symptoms including muscle spasms and abnormal muscle contractions, which resolved spontaneously or with minor interventions
doi:10.1016/j.amjoto.2019.03.017
