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Description
DEX significantly increased hepatic Keap1 expression, an established inhibitor of Nrf2 , which restricts antioxidant gene transcription by sequestering Nrf2 in the cytoplasm and promoting its degradation (Taguchi et al., 2011)
However, it is noted that the clinical outcome of ACI is still variable (Andriolo et al., 2017), and the reasons have not been fully demonstrated
Mechanics insights of curcumin in myocardial ischemia: where are we standing
It also can be used in the treatment of diabetes, to increase fat metabolism, improve skin discoloration, to fight free radicals, and to promote normal thyroid levels
