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Gene-level modulation: Pickart & Margolina 2018 documented activity across ~4,000 human genes, with fibroblast expression patterns shifting closer to younger cells
The study on polymorphisms of sep15 and TrxR2 and the expression of AP-1 signaling pathway in Kashin-Beck disease
discovered a new compound, erastin, which had a selectively lethal effect on RAS-expressing cancer cells, but the manner of cell death was different from what had been seen before
