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Cognitive-behavioral therapy Drug therapy: First-line antidepressants, including selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine [Prozac] and sertraline [Zoloft]) and serotonin-norepinephrine reuptake inhibitors (SNRIs) (eg, duloxetine [Cymbalta] and venlafaxine [Effexor]) Second-line antidepressants, including tricyclic antidepressants (TCAs) (eg, amitriptyline [Elavil] and clomipramine [Anafranil]) and monoamine oxidase inhibitors (MAOIs) (eg, tranylcypromine [Parnate] and phenelzine [Nardil]) Other antidepressants, including mirtazapine (Remeron), trazadone (Desyrel), vilazodone (Viibryd), and vortioxetine (Trintellix) Benzodiazepines such as diazepam (Valium), alprazolam (Xanax), and clonazepam (Klonopin) Buspirone (BuSpar) Hydroxyzine (Vistaril, Atarax) Pregabalin (Lyrica), an anticonvulsant drug that is also effective in treating anxiety Quetiapine (Seroquel), an antipsychotic drug that is also effective in reducing symptoms of anxiety What are Some Emerging Treatments for Anxiety Disorders