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Alternative oxidase (AOX) has an important influence on both ROS and RNS generation by the respiratory chain in mitochondria (Vanlerberghe, 2013)

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Moreover, this could help in the design of new molecules to prevent or halt lung damage in emphysema patients

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Progression of the cell cycle and proliferation sustained are two hallmarks of cancer that have an essential role in normal cells transforming into cancerous ones and the progression of the tumor (Hanahan and Weinberg, 2000)

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However, the cumbersome process of cell culture expansion and the inherently low exosome yield limit the clinical translatability of these systems [35]

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