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362 Considering the expression of the GLP-1R in thyroid C cells and the ability of GLP-1 to stimulate calcitonin secretion through a cAMP-mediated mechanism in vitro, it is plausible that calcitonin plays a role in the alterations in bone metabolism observed in GLP-1R-treated animals

The synthesis of metal nanoparticles has been widely discussed in the literature due to their distinctive chemical and physical properties, which have many potential purposes [2, 3]

Zhao G, Yuan H, Li Q, Zhang J, Guo Y, Feng T, et al

Clinical evidence comes in tiers: mechanistic studies (does the molecule do what it should at the cellular level?), animal studies (does it produce the expected effect in a living organism?), and human trials (does it actually work on the people who will use it?)