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SHMT2 played a role in regulating the stability of HIF1, which functioned as a key regulator of hypoxia-induced genes and subsequently impacts downstream VEGF and STAT3 signaling pathways [132], which also contributed to the angiogenesis in the TME [133]
The modification of miRNA expression patterns resulting from HPs60 therapy influenced the alterations in cell viability through modulating cell cycle progression as well as apoptosis (488)
hdl:10665/325771
As melatonin levels decrease, the impact on cyclic nucleotide signalling could lead to several age-related health problems, underscoring melatonins role in preserving physiological equilibrium throughout ones life
