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Nevertheless, the Prohibited List is updated annually and covers a wide range of substances and drugs, posing a challenge as the use of numerous medications used to treat diseases may alone or combined result in the presence of metabolites associated with potential anti-doping rule violations

Curr Neuropharmacol 9:195199 Suchy J, Chan A, Shea TB (2009) Dietary supplementation with a combination of alpha-lipoic acid, acetyl-l-carnitine, glycerophosphocoline, docosahexaenoic acid, and phosphatidylserine reduces oxidative damage to murine brain and improves cognitive performance

Major metabolites found were trimethylamine N-oxide, primarily in urine (8% to 49% of the administered dose) and [ 3 H]--butyrobetaine, primarily in feces (0.44% to 45% of the administered dose)

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