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Increased intracellular Ca 2+ levels are associated with the generation of oxidative stress and neurotoxicity (Lafon-Cazal, 1993

Triheptanoin for the treatment of brain energy deficit: a 14-year experience

While excessive ROS production leads to many metabolic complications in human health problems, including type II diabetes (Giacco and Brownlee, 2010), it has been increasingly recognized that physiological levels of ROS, mainly H 2 O 2 , play important roles in cellular functions that are linked with the regulation of several cellular activities, including cellular signaling, cell differentiation, and cell proliferation (Schieber and Chandel, 2014)

[DOI] [PMC free article] [PubMed] [Google Scholar] 99.Murphy T.H., Miyamoto M., Sastre A., Schnaar R.L., Coyle J.T
