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Studies published in The American Journal of Clinical Nutrition have demonstrated that regular L-Carnitine supplementation can enhance the bodys ability to burn fat during exercise by increasing fatty acid oxidation

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Deficiency of Se or its excess with dysfunction of mitochondria (organelles that contain selenoproteins) leads to thyroid disorders (65)

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MOTS-c also activates AMPK in muscle and improves mitochondrial function, which supports training capacity when calories are low

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In clinical practice, several drugs are used for CIPN, such as pregabalin, tricyclic antidepressants, and serotonin-noradrenaline reuptake inhibitors

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