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The class thought I was either mad or hardcore but if I stopped doing everything with even the less painful headaches, I would never do anything

Heterogeneity of the illness, not only in terms of phenomenology (persistent primary negative symptoms or acute psychotic exacerbation) or course (early vs late), but also abscense of putative endophenotypes (increased striatal glutamate, reduced mismatch negativity), is a common post-hoc explanation for negative RCT findings

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Here's why the combination works better than either one alone