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The sustained IGF-1 elevation maintains muscle protein synthesis rates throughout the day, which benefits subjects with severe muscle wasting

doi: 10.1172/JCI1112 79 DakinSGMartinezFOYappCWellsGOppermannUDeanBJFet al

A 1 mg/mL stock (approximately 220 M for cagrilintide) is a practical starting concentration that allows serial dilution to the nanomolar concentrations used in receptor binding and cell-based assays
