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Description
ANDREA TRAINA: As soon as you ingest food, your body is going to start secreting GLP-1 because it immediately triggers that, oh, you've ingested some food

The following is a brief summary of available data from the PIONEER 1-8 studies
Liraglutide treatment ameliorates IL-1-induced ROS production in cardiomyocytes, protects against IL-1-induced loss of mitochondrial membrane potential and decreased ATP generation, and counteracts IL-1-induced alterations in AMPK and acetyl-CoA carboxylase phosphorylation as well as the reduction of peroxisome proliferator-activated receptor coactivator-1 (PGC-1), which is a key regulator whose downregulation leads to cardiac mitochondrial dysfunction (168)

What the Gila monster evolved over millions of years, a persistent New York endocrinologist named John Eng recognized in the 1980s as a potential key to unlocking one of medicines most persistent challenges: type 2 diabetes
