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However, this change was not conserved in female WT or GLPDRKO mice (Supplementary Fig

Patients should work closely with their healthcare provider to adjust other diabetes medications appropriately and monitor glucose levels more frequently during this transition period

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This first became apparent in 2023 when the company shared the results from a phase 2 trial : study participants who ramped up to 12 mg (the highest dose) lost up to 24% of their body weight in a little less than a year
