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Diabetologia (2010) 53(1):1539

One of its primary effects is on fat, fibers, and muscle mass, which naturally decline with age
Once lymph enters the initial lymphatics, some of the key factors that determine efficient lymph transport along the collecting lymphatic vasculature are 1) efficient contractility, 2) the ability of collecting lymphatics to properly vasodilate as part of the contraction cycle, 3) competent intraluminal valves, and 4) a relative low permeability that ensures lymph remains within the lymphatic vasculature

Kuodza, G
