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Most patients lose 2-5 pounds in month one, primarily from reduced appetite and water weight

Food and Drug Administration approved Zepbound (tirzepatide) injection for chronic weight management in adults with obesity (body mass index of 30 kilograms per square meter (kg/m Obesity and overweight are serious conditions that can be associated with some of the leading causes of death such as heart disease, stroke and diabetes, said John Sharretts, M.D., director of the Division of Diabetes, Lipid Disorders, and Obesity in the FDAs Center for Drug Evaluation and Research