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However, another study by Cantini et al., used GLP-1(7-36), GLP-1(9-36) and Liraglutide to induce apoptosis in unstressed hASC, as assessed in annexin-V expression on the surface, though only the effect of Liraglutide and GLP-1(7-36) was partially reversed by the GLP-1-R-Antagonist Exendin(9-36), supporting receptor-specific activity [12]

The widespread use of weekly injectable GLP-1RA has improved acceptability of this therapy

Mering and Minkowski's findings encouraged Gustave-douard Laguesse, a French histologist and pathologist, to theorise in 1893 that the pancreatic islets described by Langerhans produced an endocrine secretion (Hoet)

Each technology offers potential benefits like improved bioavailability or better absorption sites, but also faces challenges such as manufacturing difficulties, high costs, and regulatory hurdles