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It has a short circulating half-life of approximately seven minutes due to rapid degradation by dipeptidyl peptidase IV (DPP-IV) (5659)
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Some data suggests that higher doses of tirzepatide may be associated with a higher risk of gastrointestinal issues compared to semaglutide
The proportion of GLP-1R occurring in non-stellate cells is higher when the inflammation is mild (76% AP, Figure 3a
