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The participants were all classified as either overweight or having obesity, with an average baseline weight of 248.5 pounds
Further supporting the role of Pax6 in regulating intestinal Gcg expression, adenoviral overexpression of Pax6 enhances Gcg promoter activity and Gcg expression in intestinal enteroendocrine cells such as the secretin tumor cell line-1 (STC-1) and cells derived from colonic tumors of transgenic mice expressing large T antigen under the control of the proglucagon promoter (GLUTag cells) [108]
It attacks obesity from two directions instead of one
[DOI] [PubMed] [Google Scholar] 88.Heerspink H, et al
