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DKD is considered to occur as a result of an interplay between metabolic and hemodynamic factors (58), with many of the putative pathways leading to injury having already been delineated (59)

162 ER stress plays a complex role in the control of neuronal survival, amyloid cascade, neurodegeneration, and synaptic function in AD
Remember, weight loss is not always linear, and fluctuations are normal

Think of it as managing a chronic condition, not a short-term fix
