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Description
For patients on tirzepatide, which produces a more pronounced caloric deficit due to its dual GIP/GLP-1 mechanism, methylated B12 provides upgraded energy and cognitive support during the weight loss phase

Long-term (months to years), the freezer at -20 degrees Celsius preserves potency best

In rats, several studies have shown that native GLP1 administered intraperitoneally (i.p.) requires intact vagal afferents to cause satiation, that is, to reduce meal size (Ruttimann et al., 2009)

Clinical research has confirmed no effect on IGF-1 levels and no negative impact on carbohydrate metabolism