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Alzheimer's disease (AD) is a complex multifactorial disease, and findings suggest that addressing several pathophysiological drivers may be required to maximize clinical effect

The search strategy combined keywords and Medical Subject Headings (MeSH) terms related to: (glucagon-like peptide 1 receptor agonist OR GLP-1RA OR incretins) AND (diabetes mellitus OR diabetes mellitus type 2 OR T2DM OR diabetic kidney disease) AND (albuminuria OR non-albuminuric diabetic kidney disease OR renal outcomes OR renal pathology) AND (precision medicine OR personalized medicine)

The Butsch data showed deficiencies roughly doubling between the 6- and 12-month marks

And for others, it can help them taper off a GLP-1 while reducing their risk of rebound weight gain especially if they pair it with other lifestyle changes like regular physical activity and a nutritious diet