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Indeed, nicotine evoked intense and sustained irritation and vigorous coughing in comparison to placebo, which induced no irritation and few coughs

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In conjunction with mitochondrial changes, the authors indicate that there is a significant increase in DNA damage and DNA fragmentation, suggesting there may be long-term effects associated with e-cigarette use [69]

reusable e-cigarettes - ecological & cheaper Disposable e-cigarettes have one major disadvantage: they are very unecological, as the entire device has to be disposed of as soon as the liquid has been used up