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The reasons for these seemingly opposite effects of prenatal exposure to cigarette smoke on DNA methylation in placental and fetal tissues are not clear at present
However, limited research has focused on investigating the correlates of smoking intensity, which underscores the importance of considering the number of cigarettes smoked per day as a count response variable and exploring the factors related to it [31,32,33,34]

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What matters is the total e-liquid, not the puff number on the box
