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Description
Studies have shown that acute exposure to e-cigarette aerosol increases markers of oxidative stress and inflammation in human subjects, such as C-reactive protein and soluble intercellular adhesion molecule (sICAM), peaking within 1-2 hours and returning to baseline levels after 6 hours

In corresponding males the increase was not significant

They tested their urine and saliva and asked questions about cigarette use

Cigarettes, however, were only beginning to spread, influenced in part by practices from the Ottoman Empire
