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People with chronic pain are about twice as likely to smoke cigarettes and to use other types of tobacco products, including e-cigarettes, and to use multiple products together. Powers and her colleagues analyzed a decade of smoking data from the National Health Interview Survey, which monitors the health of the U.S

While it is impossible to fully separate the effects of age at initiation and smoking duration 30 , this interaction suggests the possibility that the same quantity of smoking may raise relative cardiovascular risk to a greater extent when exposed at an earlier age

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