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The NIVELACUSO code, ingeniously simple in its construction, encapsulates three critical pieces of information: Name of the Production Factory: Each factory had its unique identifier within the code, linking every box back to its place of origin

A similar method was used to determined 210 Po and 210 Pb in the mainstream smoke of the IQOS system, except that 10 cigarettes were smoked in a run to make one sample to increase the sensitivity

Direct comparison is inexact because: puff duration varies (2-second vape puff vs 1-second cigarette drag), nicotine absorption differs (lungs vs vapor), device power affects delivery, individual technique varies, and cigarettes deliver additional chemicals enhancing absorption

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