is cigarette smoke a solute or solvent contains more than 7,000 chemicals, and hundreds of them can harm the body. Some of the most well known include: • Carbon monoxide – reduces oxygen in the blood Smokeless cigarette claims raise questions

Inclusion criteria Participant is willing and able to give informed consent for participation in the study Aged 18 years or above Current smoker with a value of at least 10 parts per million (ppm) for exhaled carbon monoxide (CO) and smokes a minimum of eight cigarettes/8 g of tobacco per day (including pipe, cigars or tobacco roll-ups) Diagnosed with one or more of the following chronic conditions: ischaemic heart disease, peripheral vascular disease, hypertension, diabetes mellitus (type 1 and type 2), stroke, asthma, COPD, chronic kidney disease, depression, schizophrenia, bipolar disorder or other psychoses Exclusion criteria GP believes that switching to e-cigarettes would not benefit the patient given their current medical condition Currently using e-cigarettes, nicotine replacement therapy or other cessation therapies (e.g

To date, nearly 600 scientific papers reporting the research have been published by grant recipients

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