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[32] Nicotine pouches [edit] On January 16, 2025, the FDA authorized several ZYN nicotine pouch products, including flavored varieties, via the Premarket Tobacco Product Application (PMTA) process

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Hence, marijuana could be the compound used by youth to self-medicate for anxiety, which might explain why, in our study, e-cigarette use alone is associated with depression/ anxiety comorbidity while e-cigarette use with marijuana is associated with MDS only