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However, it remains unclear whether similar changes in the PC phenotype occur in the aging cochlea and how these alterations might contribute to the thickening of the basement membrane during the aging process
Mol Chem Neuropathol 1991

In THyPRP silenced plants, a decrease in expression for ethylene biosynthesis genes, including ACS, ACO, most likely results in reduced ethylene production in the AZ, which inhibits the acquisition of the competence of the AZ cells to respond to ethylene signaling

Therefore, this technology searches for the motif sequence complementary to the crRNA of gRNA in the target DNA molecule with a PAM sequence behind it
