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In the fasting state, normal mitochondria preferentially oxidize fatty-acids, and mitochondrial function is impaired in aging (17,21)

This is especially true in the center of the adult lens, known as the nucleus, where even small amounts of UV exposure can drive free radical formation and the generation of cataracts (Giblin 2000

Teeth missing more than 50% of their of structure or are cracked, need zirconia crowns in addition to fillings

1 In contrast, quiescent cells can reenter the cell cycle, and differentiated cells can be dedifferentiated under certain circumstances
