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465 Furthermore, administration of nanomicellar curcumin (80 mg/day) for 3 months reduced the VAS score, CRP, CD4 + and CD8 + Th17 cells, and B cells, and increased Treg cells in osteoarthritis

The imbalance between these metabolic pathways results in an elevation of HCY levels in the bloodstream, leading to hyperhomocysteinemia [294]
