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doi: 10.1016/j.freeradbiomed.2018.12.011 21 SabatierMBirsenRLautureLMoucheSAngelinoPDehairsJet al
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By modulating the chromatin structure and accessibility of the NRF2 promoter, epigenetic modifications determine how effectively NRF2 can be activated in response to various cellular stresses
This deficit in mitochondrial energy reserve is well-documented in clinical literature [1]
