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It is proposed that this downregulation of the central carbon metabolism triggers changes to the growth form as a result of less energy being available, and consequently impacts filamentous growth

The care of the animals was in accordance with the standard operating procedures of the facility for pharmacological animals and the European Convention for the Protection of Vertebrate Animals Used for Experimental and Other Scientific Purposes (ETS 123)

Conversely, there is an increase in CD56 dim cells, which are predominantly cytotoxic [196,197,198]

In addition, phosphofructokinase liver type, a glycolytic enzyme, has been shown to activate CPT1A, thereby promoting FAO and tumor growth [302]