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Continuous dosing without a break blunts receptor sensitivity and reduces the efficacy of subsequent cycles

Payment varies by setting Hospital Outpatient Departments (HOPD) typically receive higher reimbursement than Ambulatory Surgical Centers (ASC) , reflecting different overhead costs

Advise patients that there is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to trazodone during pregnancy [see Use in Special Populations ( 8.1)]

The appetite-suppressing effects of these medications, coupled with their ability to slow gastric emptying and induce a prolonged feeling of fullness, contribute to reduced food intake and subsequent weight reduction