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Plant Biotechnol J 14(1):821 Moghrovyan A, Parseghyan L, Sevoyan G, Darbinyan A, Sahakyan N, Gaboyan M, Karabekian Z, Voskanyan A (2022) Antinociceptive, anti-inflammatory, and cytotoxic properties of Origanum vulgare essential oil, rich with -caryophyllene and -caryophyllene oxide

The authors believed these mutations would be devastating and have progressive effects on ATP production and mitochondrial functions

In short, any dosing figure circulating for dogs is an extrapolation, not a validated veterinary protocol

10.1039/c5fo01101a 23
