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DISCUSSION Endothelial dysfunction and impaired NO signaling are common contributors to ED [8]

As synaptic plasticity is impaired, or otherwise maladaptive, in various neuropsychiatric disorders [182,183] including depression [184], its facilitation by BDNF represents an important potential therapeutic mechanism

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Neuronal differentiation and maturation assay MGF overexpressing mice (M mice) and control (R mice), were injected with BrdU (50 mg/kg body weight, once daily at 10 a.m.) for 1 week and sacrificed 4 weeks after the first BrdU injection