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This is because both compounds affect gastrointestinal motility and appetite through their respective mechanisms, and layering them too aggressively creates compounding GI effects that can derail compliance

The lack of FDA approval for these specific uses means that they are not subject to the same rigorous testing and oversight as traditional pharmaceuticals

Sermorelin requires a functional pituitary to be effective and will not work in cases of pituitary damage or primary GH gene defects
