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Symptoms indicative of liver disease include: Digestive Issues : Watch for constipation, diarrhea, gas, or bloating, which are abnormal and should not persist
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Cappellini MD, Fiorelli G (2008) Glucose-6-phosphate dehydrogenase deficiency
However, this effect is typically less robust than reduction of drug self-administration and is observed with higher doses of agonist than the minimal effective dose required to reduce drug self-administration (Peters and Kalivas, 2006
