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Thus, in this study, we leveraged multivariate data analysis (MVDA) and flux balance analysis (FBA) with explainable AI (xAI) to mechanistically characterize the phenotypic differentiation between early (EP) and late passage (LP) of CHO cultures

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The key TMA-generating step is catalyzed by a previously unknown type of TMA-lyase enzyme that utilizes a flavin cofactor to catalyze a redox neutral transformation

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