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Description
VPA, in addition to raising GABA levels, may have an antiepileptic effect via lowering the high-frequency firing of neurons by closing calcium, sodium, and potassium voltage-gated channels (along with those that were coded by CACNA1C, CACNA1N, CACNA1D, also the SCN and CACNA1F family of genes) (Van den Berg et al., 1993)

10.1039/d4qm00935e 34 LiS.LiJ.XingJ.LiL.WangL.WangC

van Schie RM, et al

These nanoformulated astaxanthin systems demonstrated acceptable biocompatibility and exerted antioxidant and anti-inflammatory effects in neural cell models, supporting their potential utility for neuroprotective applications