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Noteworthy, the TAA prediction showed a strong and better concordance with respect to neoantigens with proteomic data

In experimental studies, formation of complexes of cellular antigen with antibody resulted in activation of dendritic cells, facilitation of cross-presentation of antigens to tumor-specific CD 8 + T cells and inhibition of tumor growth Fc receptor-targeted antigen uptake was shown to initiate cross-presentation pathways as an immune regulatory mechanism for effective tumor immunity

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