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[36] If no relief is found through these initial treatment methods or symptoms have worsened, allergy patch tests should be considered in order to explore the possibility that allergy cheilitis is the cause, in this case avoidance of the allergen would be the best course of treatment

Researchers have identified two pharmacophores (sequences of three amino acids) within peptide inhibitor of transendothelial migration (PEPITEM), a 14animo acid peptide that is released by B lymphocytes during an inflammatory response, such as with psoriasis