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Retrieved 23 January 2020

By stimulating collagen production and improving circulation, the Cryoskin Facial lifts and tightens the skin, shrinks pores, reduces fine lines, and leaves the complexion looking refreshed and radiant with no downtime

Significantly, histone crotonylation induces a heightened relaxation of chromatin architecture and exerts a more potent stimulatory effect on gene expression compared to acetylation

Despite its widespread use and acceptance, this methodology has been criticized for being labor-intensive and for its inability to detect microorganisms that cannot be cultured in the laboratory 7,16
