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Recent comparative evolutionary analysis of ABHD5 and closely related paralog ABHD4 identified critical surface residues of R299 and G328 that are required for lipase activation of PNPLA2, which can be dissociated from translocation of PNPLA2 (34)
the null allele produces no 1 -antitrypsin
Keep indoor humidity between 3050% with a dehumidifier in vulnerable rooms
