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Description
Obesity and cardiovascular disease: the emerging role of inflammation
The authors employed cellulose-based purification to remove dsRNA byproducts, yielding high-purity saRNA preparations
These DAMPs stimulate Pattern Recognition Receptors (PRRs) and the NLRP3 inflammasome, promoting persistent neuroinflammation (91)
Additionally, a 6-month intervention with oral ALA (600 mg/day) significantly reduced advanced glycation end products (AGEs), increased the current perception threshold and granulocyte protein levels, and decreased asymmetric dimethylarginine (ADMA), thereby improving vascular endothelial function and alleviating the neuropathic symptoms of type 2 diabetes mellitus (T2DM) patients with neuropathy [66]
