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In LPS-induced acute lung injury of mice, ISA could inhibit PI3K/AKT signaling and upregulate Nrf2/HO-1 pathway, leading to the inhibition of NF-B signaling

Glutamine therapy improves outcome of in vitro and in vivo experimental colitis models
Breder, A

however it nonetheless suggests that the production of these two sulphur-containing, redox-active metabolites is interlinked
