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Description
Mar 15 2017;13(3):479-504
This involves inhibition of Akt1 activation, mediated by the increased ROS
Metformin-related vitamin B12 deficiency occurs as metformin causes reduced vitamin B12 absorption by interfering with the vitamin B12-intrinsic factor complex
A interacts with microglial receptors activating downstream pathways that cause mitochondrial damage and exacerbate inflammation and cytotoxicity
